TNPSC 2005 – QUESTION PAPER

TNPSC 2005 – QUESTION PAPER
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1. Longest telomeres are found in which
cells?
a. Nerve cell
b. Retinal cell
c. Sperms
d. Skeletal muscle cell
2. Conjugated Hyper-bilirubinemia is found
in the following conditions, except
a. Dubin- Johnson syndrome
b. Criggler – Najjar syndrome
c. Rotor Syndrome
d. Gilbert syndrome
3. Virchow’s Node is located in the
a. Axilla
b. Mediastinum
c. Left Supraclavicular region
d. Sub-mandibular region
4. Carcinoma Prostate is characterized by
the following, except
a. androgen receptors
b. osteolytic secondaries
c. perineural invasion
d. single layer of cells
5. AIDS virus belongs to
a. Lassa virus
b. Lentic virus
c. Pox virus
d. Myxo virus
6. The commonest site of Tuberculosis in
the GIT is
a. Stomach
b. Jejunum
c. Ileo-cecal region
d. Colon
7. The histological type of Bronchogenic
carcinoma in smokers is
a. Squamous cell carcinoma
b. Small cell carcinoma
c. Adenocarcinoma
d. Undifferentiated carcinoma
8. Which one of the following is correctly
matched?
a. Urothelial carcinoma - Transitional cells
b. Renal cell carcinoma - Blastemal cells
c. Nephroblastoma - Eosinophilic cells
d. Oncocytoma - Clear cells
9. Which one of the following is correctly
matched?
a. X-linked recessive disorder - Glycogen
storage disease
b. Autosomal dominant disorder -
Hemophilia A
c. Autosomal recessive disorder - Sickle
cell anemia
d. Metabolic disorder - Hereditary
spherocytosis
10. The sequence of events in
Carcinogenesis is
a. Mutation in the genome, DNA damage,
Malignant neoplasm, Expression of altered
gene products.
b. Mutation in the Genome, DNA damage,
Expression of the altered gene products,
Malignant neoplasm
c. DNA damage, Expression of the altered
gene products, Mutation in the Genome,
Malignant neoplasm
d. DNA damage, Mutation in the genome,
Expression of the altered gene products,
Malignant neoplasm.
11. In Hemoglobin degradation, the first bile
pigment formed is
a. Bilirubin b. Biliverdin
c. Bile acids d. Cholic acids
12. In Hepatic Jaundice with cholestasis,
urine contains
a. high levels of conjugated bilirubin and
urobilinogen
b. high leves of conjugated bilirubin and
negligible urobilinogen
c. high levels of unconjugated bilirubin and
urobilinogen
d. high levels of unconjugated bilirubin and
negligible urobilinogen.
13. Following are the examples of
Unconjugated Hyperbilirubinemia except
a. Gilbert syndrome
b. Dubin – Johnson syndrome
c. Crigler – Najjar syndrome
d. Lucey – Driscoll syndrome
14. The Chloride Shift involves
a. K+ accompanying each bicarbonate that
leaves the erythrocyte
b. Carbonic acid leaving the erythrocyte
c. Bicarbonate leaving the erythrocyte in
exchange for chloride
d. Protons leaving the erythrocyte for each
Co2 that enters